What are the causes of mild splenomegaly?

An enlarged spleen can be caused by a number of diseases and conditions. Infections, such as mononucleosis, are among the most common causes of splenomegaly. Problems with your liver, such as cirrhosis and cystic fibrosis, can also cause an enlarged spleen. Hodgkin’s disease.

Besides, why would your spleen be enlarged?

Causes of an Enlarged Spleen. An enlarged spleen can be caused by infections, cirrhosis and other liver diseases, blood diseases characterized by abnormal blood cells, problems with the lymph system, or other conditions.

What causes massive splenomegaly?

Splenomegaly may also come from bacterial infections, such as syphilis or an infection of the heart’s inner lining (endocarditis). The causes of massive splenomegaly (spleen >1000 g) are fewer, and include: visceral leishmaniasis (kala-azar) chronic myelogenous leukemia.

How is splenomegaly treated?

Pharmacologic Therapy. Chemotherapy is used for hematologic malignancies. Antibiotics are used for infection, with the exception of infection associated with a splenic abscess; this requires surgical intervention. Immunosuppression is used for autoimmune or inflammatory disorders, treatment of cirrhosis, and CHF.

What is the normal spleen size in an ultrasound?

Diagnostic imaging to assess spleen size is routinely accomplished by ultrasonographic measurement along its long axis. However, there is variation among radiological texts in defining the upper limits of normal for longitudinal diameter, with values ranging from 12 to 14 cm in adults.

Why does splenomegaly cause thrombocytopenia?

Increased splenic platelet sequestration can occur in various disorders that cause splenomegaly However, thrombocytopenia that occurs in advanced cirrhosis is mostly due to reduced thrombopoietin production by the liver (and consequent reduced platelet production) rather than splenic sequestration (1).

What could lead to a splenectomy?

Splenectomy is a surgical procedure to remove your spleen. The spleen is an organ that sits under your rib cage on the upper left side of your abdomen. It helps fight infection and filters unneeded material, such as old or damaged blood cells.

How does cirrhosis cause splenomegaly?

Causes of splenomegaly. Since the spleen is involved in so many bodily functions, it is vulnerable to a wide range of disorders. Some of the causes of splenomegaly include: Cirrhosis of the liver – which can increase the blood pressure inside the vessels of the spleen.

Why does the spleen enlarge?

Causes of an Enlarged Spleen. An enlarged spleen can be caused by infections, cirrhosis and other liver diseases, blood diseases characterized by abnormal blood cells, problems with the lymph system, or other conditions.

How does splenomegaly cause portal hypertension?

Portal hypertension results mainly from increased resistance to blood flow in the portal vein. A common cause of this resistance is disease within the liver; uncommon causes include blockage of the splenic or portal vein and impaired hepatic venous outflow (see Table: Most Common Causes of Portal Hypertension).

What is hepatomegaly and splenomegaly?

Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).

How is splenomegaly treated?

Pharmacologic Therapy. Chemotherapy is used for hematologic malignancies. Antibiotics are used for infection, with the exception of infection associated with a splenic abscess; this requires surgical intervention. Immunosuppression is used for autoimmune or inflammatory disorders, treatment of cirrhosis, and CHF.

Is an enlarged spleen serious?

Your spleen is an organ located just below your left rib cage. Many conditions — including infections, liver disease and some cancers — can cause an enlarged spleen, also known as splenomegaly (spleh-no-MEG-uh-lee). An enlarged spleen usually doesn’t cause symptoms.

Can you live with a enlarged spleen?

If an enlarged spleen causes serious complications or the cause can’t be identified or treated, surgical removal of your spleen (splenectomy) may be an option. You can live an active life without a spleen, but you’re more likely to contract serious or even life-threatening infections after spleen removal.

What does palpable spleen mean?

Splenomegaly is an enlargement of the spleen. The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen. It is therefore not surprising that splenomegaly is associated with any disease process that involves abnormal red blood cells being destroyed in the spleen.

Can you live without a spleen?

Technically, people can live with no kidneys, but require dialysis. Spleen: The spleen filters blood and helps the body fight infections, but it’s not essential for survival. The spleen can be removed if, for instance, it’s damaged. However, people without a spleen are more prone to infections.

How do you feel for an enlarged spleen?

To detect splenomegaly, place the examining hand flat on the abdomen as before, well below the left costal margin. Press inwards and upwards and ask the patient to breathe in again. An enlarged spleen should be felt against the fingertips.

What are the symptoms of cancer of the spleen?

The most common symptoms of spleen cancer are:

  • enlarged spleen, which may become twice as large as normal.
  • pain in the abdomen, usually in the upper left corner.
  • weakness.
  • unexplained weight loss.
  • fatigue.
  • fever.
  • night sweats.
  • high levels of lymphocytes in the blood.
  • Where do you feel spleen pain?

    Symptoms you may experience with an enlarged spleen include: pressure or pain in the left upper part of your abdomen (near the stomach), feeling full without eating a large meal, or pain your left shoulder blade or shoulder area when taking a deep breath.

    What is splenomegaly disease?

    The causes of splenomegaly vary widely and range from malignancy (cancers), infections, congestion (increased blood flow), infiltration of the spleen from other diseases, inflammatory conditions, and blood cell diseases.

    What is the definition of massive splenomegaly?

    Massive splenomegaly is usually defined as a spleen ex- tending well into the left lower quadrant or pelvis or which has crossed the midline of the abdomen. Chronic leukemias were associated most frequently with massive splenomegaly.

    What are the causes of pancytopenia?

    Some of the conditions that can cause pancytopenia include:

  • aplastic anemia.
  • autoimmune conditions.
  • cancer.
  • chemotherapy treatments.
  • exposure to toxins or pollutants, such as radiation or arsenic.
  • Fanconi’s anemia.
  • infection.
  • leukemia, which impacts bone marrow function.
  • What do you mean by Hepatosplenomegaly?

    Hepatosplenomegaly is a disorder where both the liver and spleen swell beyond their normal size, usually due to an infection such mononucleosis or viral hepatitis. It may also be a sign of another more serious illness such as a lysosomal storage disorder.